Paracetamol intravenous solution:
Paracetamol Pharco B Vial 1% - 100 ml is considered a non-narcotic analgesic, antipyretic, analgesic and antipyretic. It is most active on the enzyme cyclooxygenase in the brain. Peripherally it is a weak inhibitor of prostaglandin synthesis.
Mechanism of action of paracetamol:
Paracetamol has an analgesic and antipyretic effect. It is most active on the enzyme cyclooxygenase in the brain. Peripherally it is a weak inhibitor of prostaglandin synthesis.
Analgesic effect:
Paracetamol raises the pain threshold and produces an analgesic effect.
Antipyretic effect:
Paracetamol reduces fever by directly affecting the thermoregulation center in the hypothalamus and blocking the effects of endogenous pyrogens.
Indications for the use of paracetamol:
1. To relieve pain and fever
2. Acute gout
3. Interactions of paracetamol with cholestyramine in migraine: Decreased absorption of paracetamol.
Charcoal: Activated and given immediately, it reduces the absorption of paracetamol.
Domperidone and metoclopramide: enhance the absorption of paracetamol.
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