Combiglyze XR 5 mg/1000 mg 30 tablets Combiglyze
How saxagliptin and metformin work
- Saxagliptin is an inhibitor of DPP-4, an enzyme that degrades incretin hormones including glucagon-like peptide-1 (GLP-1).
- Incretin helps the body produce more insulin only when it is needed and reduces the amount of glucose produced by the liver
- Metformin reduces blood glucose levels by decreasing glucose production in the liver
- Metformin reduces intestinal absorption of glucose
- Metformin increases insulin sensitivity resulting in increased glucose uptake and utilization
Medical uses of Combiglyz XR 1000/5 tablets
- This medication is used to treat a type of diabetes called “type 2 diabetes.”
- Saxagliptin and metformin work together to control blood sugar.
- Increases postprandial insulin levels. It also reduces the amount of sugar your body makes in the liver.
- Along with diet and exercise, this medication helps lower blood sugar.
- This medication may be used alone or with other antidiabetic medications, including insulin.
How to use Combiglyz XR 1000/5 Tablets
- Always take this medication exactly as your doctor has told you. Consult your doctor or pharmacist if you are not sure.
- If your doctor has prescribed this medication with a sulfonylurea or insulin, remember to take this other medication as directed by your doctor for the best results for your health.
- The amount of this medication you will take will vary depending on your condition
- Your doctor will tell you exactly what dose of this medicine to take.
- Recommended doses are one tablet twice a day.
- If you have poor kidney function, your doctor may prescribe a lower dose.
- Take this medication orally.
- Take it with a meal to reduce your chance of stomach upset (a side effect of the medication).
- Doses may be changed in special circumstances, so always follow your doctor or pharmacist's instructions.
- If you take more medicine than you should, talk to your doctor or go to hospital straight away.
- If you forget to take a dose, take it as soon as you remember unless it is almost time for your next dose
- Do not take a double dose (two doses at the same time) to make up for a missed dose.
