Glucovance 500mg/5mg Glibenclamide/Metformin Hydrochloride The combination Glibenclamide/Metformin Hydrochloride is used to lower blood sugar levels in type 2 (non-insulin dependent) diabetes as an addition to a proper diet and exercise.
Glucovance 500/5 tablets to
- Oral diabetes medications
How glibenclamide and metformin work
- Like all sulfonylureas, glibenclamide acts as a suppressor of insulin secretion. It lowers blood sugar by stimulating insulin secretion by pancreatic beta cells and by stimulating increased activity of insulin receptors within the cells
- Metformin reduces blood glucose levels by decreasing glucose production in the liver
- Metformin reduces intestinal absorption of glucose
- Metformin increases insulin sensitivity resulting in increased glucose uptake and utilization
Medical uses of Glucovance 500/5 tablets
- It is used to lower blood sugar levels in people with type 2 diabetes (non-insulin dependent). It is used when diet and exercise alone fail to control diabetes.
How to use Glucovance 500/5 Tablets
- This medicine is intended for adults only.
- Take it as directed by your doctor.
- Take the medicine with meals.
- It is important to follow the diet and exercise plan prescribed by your doctor while continuing treatment
- The usual starting dose is glibenclamide 1.25-2.5 mg/metformin 500-1000 mg. It is given once or twice daily.
- Doses may be changed in special circumstances, so always follow your doctor or pharmacist's instructions.
- If you take more medicine than you should, talk to your doctor or go to hospital straight away.
- If you forget to take a dose, take it as soon as you remember unless it is almost time for your next dose
- Do not take a double dose (two doses at the same time) to make up for a missed dose.
Side effects of Glucovance 500/5 tablets
- Although the following side effects are not common in everyone, some patients may report:
- Decrease in the number of blood cells (platelets, red and white blood cells)
- nausea
- Diarrhea
- Eyesight and vision problems
- sensitive
- Low blood sugar levels
- Liver problems
Use of Glucovance 500/5 tablets during pregnancy and lactation
- If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
- Your doctor will discuss the potential risks and benefits of using this medication during pregnancy and breast-feeding
